Structural and mechanical characterization of crosslinked and sterilised nanocellulose-based hydrogels for cartilage tissue engineering

Mechanical Characterisation of Hydrogels for Tissue Engineering

Hydrogels Containing Marine Polysaccharides For Bone and Cartilage Tissue Engineering

Introduction: The most common biopolymers used to build-up 3D scaffolds for bone and cartilage tissue engineering are chitosan, alginate, cellulose derivatives, hyaluronic acid, chondroitin sulfate, collagen and gelatin. In this study, we propose to evaluate the potential of two new marine exopolysaccharides (HE800 and GY785) that are glycosaminoglycan-like polymers and that can be produced in ...

PEG-PLA hydrogels by stereocomplexation for tissue engineering of cartilage.

PEG–PLA hydrogels were prepared by stereocomplexation of poly(lactide) (PLA) blocks of opposite chirality. Gelation occurred upon mixing aqueous solutions of both enantiomers of PEG6500–(PLA)2, PEG12500–(PLA)2 and PEG21800–(PLA)8 block copolymers. Stereocomplexed hydrogels from PEG6500–(PLA)2 polymers were found to be stable up to ~37 8C, while those from PEG12500–(PLA)2 and PEG21800–(PLA)8 blo...

Fabrication and characterization of nanofibrous tricuspid valve scaffold based on polyurethane for heart valve tissue engineering

Objective(s): Tissue engineering represents a new approach to solve the current complications of the heart valve replacements by offering viable valve prosthesis with growth and remodeling capability. In this project, electrospinning and dip coating techniques were used to fabricate heart valve constructs from medical grade polyurethane (PU). Methods: Fir...

Evaluation of Fracture Toughness for Articular Cartilage and Hydrogels in Cartilage Tissue Engineering By

Recently, biomaterials-based tissue engineering strategies such as hydrogels have offered great promise in repairing articular cartilage. Mechanical failure testing in outcome analyses is given the crucial clinical importance to the success of engineered constructs. Interpenetrating networks (IPNs) are gaining more attention due to their superior mechanical integrity. Extensive fracture toughne...